Gram Negative Acute Bacterial Meningitis an Emerging Entity in a Tertiary Care Centre, New Delhi

Submit Manuscript | http://medcraveonline.com therapy for ABM has to be initiated before the aetiology is known. The emergence of antimicrobial resistance has added to this problem, and current recommendations are to identify targets for immunization, formulate preventive strategies and to carry out a rational empirical treatment [5-9]. Among neonates, Group B and non-Group B Streptococcus species (49%), Escherichia coli (18%) and Listeria monocytogenes (7%) are the most common pathogens which are seen. The meningitis-causing pathogens which are found in infant and child age groups are Haemophilus influenzae (40-60%), Neisseria meningitidis (25-40%) and Streptococcus pneumoniae (10-20%). The common pathogens which are encountered in adult meningitis are Streptococcus pneumoniae (30-50%), Neisseria meningitidis (10-35%), Staphylococci (515%), other Streptococcus species, Haemophilus influenzae (13%), Gram negative bacilli (1-10%) and Listeria monocytogenes [10-14]. A delay in diagnosis and initiation of antimicrobial therapy can result in a poor outcome of the disease. The aim of the present study was to analyze the emerging pathogen, bacterial profiles and antimicrobial susceptibility patterns of the isolates which were obtained from CSF of patients with ABM in the given area.